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In 2016 he offered the BBC Four documentary Inside Porton Down: Britain's Secret Weapons Research Facility. Just one Thing. BBC Radio Four. Mosley was credited with popularising a form of intermittent fasting called the 5:2 weight loss plan by means of an episode of the BBC documentary collection Horizon called "Eat, Fast and Live Longer". Mosley was an advocate of intermittent fasting and low-carbohydrate diets who wrote books promoting the ketogenic weight loss plan. Mosley promoted intermittent fasting and was a low-carbohydrate weight-reduction plan advocate. Mosley advocated The Fast 800 Diet, a low-carbohydrate Mediterranean food regimen with intermittent fasting that follows a every day 800-calorie eating plan. Mosley introduced a two-half documentary, Frontline Medicine, in 2011, with episodes titled "Survival" and "Rebuilding Lives". In January 2013, Mosley introduced The Genius of Invention. In 2021, Mosley offered a three-half series, Lose a Stone in 21 Days, for Channel 4. On the programme Mosley steered that folks might lose a stone (14 lb; 6.4 kg) in 21 days by calorie restriction to solely 800 calories a day.